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1996-02-27
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Document 0057
DOCN M9630057
TI [Pruritus--also a challenge in internal medicine]
DT 9603
AU Brunner W; Medizinische Klinik, Kantonsspital Chur.
SO Schweiz Med Wochenschr. 1995 Nov 18;125(46):2244-50. Unique Identifier :
AIDSLINE MED/96091969
AB Generalized or localized itch without primary skin manifestations may be
the presenting symptom of serious internal diseases. Five characteristic
cases of pruritus are discussed: Hodgkin's disease, primary sclerosing
cholangitis, polycythemia vera, iron deficiency (with pica), and uremia.
Other important causes must be considered; all forms of cholestasis,
including primary biliary cirrhosis, drug-induced, pregnancy-related,
and extrahepatic cholestasis; other hematologic and malignant disorders
such as non-Hodgkin's lymphoma, leukemia, multiple myeloma, solid
tumors, and myelodysplastic syndromes; metabolic and endocrine diseases,
most notably diabetes mellitus, hyperthyroidism, hypothyroidism, and
carcinoid syndrome; focal neurologic diseases such as brain tumors,
cerebral infarctions and multiple sclerosis; adverse drug reactions
without rash; infectious diseases, especially parasitic and HIV
infections. A diagnostic laboratory screening for pruritus of
undetermined origin is suggested.
DE Adult Aged Anemia, Iron-Deficiency/COMPLICATIONS Case Report
Cholangitis, Sclerosing/COMPLICATIONS Diagnosis, Differential English
Abstract Female Hematologic Diseases/COMPLICATIONS Hodgkin's
Disease/COMPLICATIONS Human Liver Diseases/COMPLICATIONS Male
Metabolic Diseases/COMPLICATIONS Middle Age Pica/COMPLICATIONS
Polycythemia Vera/COMPLICATIONS Pruritus/CHEMICALLY
INDUCED/DIAGNOSIS/*ETIOLOGY Uremia/COMPLICATIONS JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).